D17
Neutron reflectometer with horizontal scattering geometry
A cationic functionalised gold nanoparticle extracting a lipid from a membrane – a potential mechanism for membrane destabilisation.
Credit: Fabio Lolicato, University of Helsinki
Scientists explore the unknown behaviour of gold nanoparticles with neutrons
Researchers investigate new interactions between gold nanoparticles and cell membranes.
Gold nanoparticles have a range of biomedical applications and are an important tool for drug delivery
Factors such as temperature and membrane charge are revealed to play a key role – findings that will help scientists better predict how gold nanoparticles behave within the body.
Re.: The role of temperature and lipid charge on intake/uptake of cationic gold nanoparticles into lipid bilayers, F. Lolicato, L. Joly, H. Martinez-Seara, G. Fragneto, E. Scoppola, F. Baldelli Bombelli, I. Vattulainen, J. Akola, M. Maccarini [doi:10.1002/smll.201805046]