Publications

2021

The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme. J Ramos, V Laux, M Haertlein, VT Forsyth, E Mossou, S Larsen, AE Langkilde. Acta Crystallographica D (2021, in press).
Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD (14/96/109). LA Perera, S Preissler, NR Zaccai, S Prévost, JM Devos, M Haertlein, & D Ron, Nature Communications 12:5004 (2021). https://doi.org/10.1038/s41467-021-25076-7.
SARS-CoV-2 Spike Protein Removes Lipids From Model Membranes and Interferes with the Capacity of High Density Lipoprotein to Exchange Lipids. YY Correa, S Waldie, M Thépaut, S Micchiula, M Moulin, F Fieschi, H Pichler, VT Forsyth, M Haertlein, M Cardenas. J. Coll. Int. Sci 602, 732-739 (2021). https://doi.org/10.1016/j.jcis.2021.06.056

Evolving origin-of-transfer sequences onstaphylococcal conjugative and mobilizableplasmids––who's mimicking whom? KY Eto, SM Kwong, PT LaBreck, JE Crow,DAK Traore, N Parahitiyawa, HM Fairhurst, DS Merrell,N Firth, CS Bond, JP Ramsay. Nucleic Acids Research 49, 5177–5188 (2021). https://doi.org/10.1093/nar/gkab303

Metabolic fluxes for nutritional flexibility of Mycobacterium tuberculosis. K Borah, TA Mendum, ND Hawkins, JK Ward, MH Beale, G Larrouy-Maumus, A Bhatt, M Moulin, M Haertlein, G Strohmeier, H Pichler, VT Forsyth. S Noack, CW Goulding, J McFadden, DJV Beste, Molecular Systems Biology17:e10280 (2021). https://doi.org/10.15252/msb.202110280
Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis. L McGregor, T Földes, S Bui, M Moulin, N Coquelle, MP Blakeley, E Rosta, RA Steiner. IUCrJ 8, 46-59 (2021). https://doi.org/10.1107/s2052252520013615
Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles. F Sebastiani, MY Arteta, M Lerche, L Porcar, C Lang, RA Bragg, CS Elmore, V Krishnamurthy, RA Russell, T Darwish, H Pichler, S Waldie, M Moulin, M Haertlein, VT Forsyth, L Lindfors, M Cárdenas. ACS Nano (2021). https://doi.org/10.1021/acsnano.0c10064
Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering. BJ Eves, J Doutch, AE Terry, H Yin, M. Moulin, M. Haertlein, VT Forsyth, P Flagmeier, DM Dias, T Knowles, G Lotze, A Seddon, AM Squires, RSC Chem. Biology (2016). https://doi.org/10.1039/D1CB00001B
ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes: Effect of Protein Isoform and Membrane Composition. S Waldie, F. Sebastiani, M. Moulin, R Del Giudice, N Paracini, F. Rossen-Runge, Y Gerelli, S Prevost, JC Voss, TA Darwish, N Yepuri, H Pichler, S Maric, VT Forsyth, M Haertlein,M Cardenas, Front. Chem. 9: 630151 (2021). https://doi.org/10.3389/fchem.2021.630152
Structural insights to protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme. J Ramos, V Laux, M Haertlein, E Erba Boeri, KE McAuley, VT Forsyth, E Mossou, S Larsen, AE Langkilde, IUCrJ 8 (2021). https://doi.org/10.1107/S2052252521001299
Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions. L Gajdos, MP Blakeley, A Kumar, M Wimmerová, M Haertlein, VT Forsyth, A Imberty, JM Devos, Structure 29, 1–11, (2021). https://doi.org/10.1016/j.str.2021.03.003
A Dimerization Site at SCR-17/18 in Factor H Clarifies a New Mechanism for Complement Regulatory Control. OM Dunne, X Gao, R Nan, J Gor, PJ Adamson, DL Gordon, M Moulin, M Haertlein, VT Forsyth, SJ Perkins, Frontiers in Immunology 11, 601895 (2021). https://doi.org/10.3389/fimmu.2020.601895
Nanostructural deformation of high-stiffness spruce wood under tension. LH Thomas, CM Altaner, VT Forsyth, E Mossou, CJ Kennedy, A Martel, MC Jarvis. Scientific Reports 11, 453 (2021). http://dx.doi.org/10.1038/s41598-020-79676-2
Production of perdeuterated fucose from glyco-engineered bacteria. L Gajdos, VT Forsyth, MP Blakeley, M Haertlein, A Imberty, E Samain, JM Devos, Glycobiology 31, 151-158 (2021). https://doi.org/10.1093/glycob/cwaa059

2020

Molecular Changes in Dengue Envelope Protein Domain III upon Interaction with Glycosaminoglycans. JG Hyatt, S Prevost, JM Devos, CJ Mycroft-West, MA Skidmore, A Winter, Pathogens (2020) 9, 935. http://dx.doi.org/10.3390/pathogens9110935
Diffusive dynamics of Aspartate α-decarboxylase (ADC) liganded with D-serine in aqueous solution. T Raskar, S Niebling, JM Devos, BA Yorke, M Härtlein, N Huse, VT Forsyth, T Seydel, AR Pearson. BioXriv doi: https://doi.org/10.1101/2020.08.11.244939
Visualizing the protons in a metalloenzyme electron proton transfer pathway. H Kwon, J Basran, JM Devos, R Suardíaz, MW van der Kamp, AJ Mulholland, TE Schrader, A Ostermann, MP Blakeley, PCE Moody, and EL Raven. PNAS 117 (12) 6484-6490 (2020).
Analytical Research Infrastructures in Europe - A key resource for the five Horizon Europe missions. Ariese Freek, Biegert Jens, Borkowski Rafal Dunin, van Breukelen Martin, Ciancio Regina, Cicchetti Gregor, van Daalen Mirjam, Daillant Jean, Dobosz Dufrénoy Sandrine, Dollinger Günther, Gleizes Pierre-Emmanuel, Facsko Stefan, Forsyth Trevor, Gunsenheimer Ute, Kirkland Angus, Kolar Jana, Krell Ute, Lyonnard Sandrine, Mitchell Ed, Pelico Primoz, Redlich Britta, Schertler Gebhard, Schneidewind Astrid, Snoeck Etienne, Synal Hans-Arno, Velegrakis Michalis, Wallner Anton, Wosnitza Jochen. https://zenodo.org/record/4049769#.X23I94u-lEY
Interdomain Flexibility within NADPH Oxidase Suggested by SANS Using LMNG Stealth Carrier. A Vermot, I Petit-Hartlein, C Breyton, A Roy, M THepaut, C Vives, M Moulin, M Hartlein, S Grudinin, SME Smith, C Ebel, A Martel, F Fieschi. Biophysical Journal. https://doi.org/10.1016/j.bpj.2020.06.025
Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol. Sarah Waldie, Federica Sebastiani, Kathryn Browning, Selma Maric, Tania K. Lind, Nageshwar Yepuri, Tamim A. Darwish, Martine Moulin, Gernot Strohmeier, Harald Pichler, Maximilian W.A. Skoda, Armando Maestro, Michael Haertlein, V. Trevor Forsyth, Eva Bengtsson, Martin Malmsten, Marité Cárdenas. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1865 (10), (2020). https://doi.org/10.1016/j.bbalip.2020.158769
Neutron scattering for structural biology. D Hoogerheide, VT Forsyth, KA Brown. Physics Today 73 (6), 36-43 (2020). https://doi.org/10.1063/PT.3.4498
Neutron radiobiology studies with a pure cold neutron beam. M Pedrosa-Rivera, MJ Ruiz-Magaña, I Porras, J Praena, P Torres-Sánchez, MP Sabariego, U Köster, T Forsyth, T Soldner, M Haertlein, C Ruiz-Ruiz. Nuc. Instr. Meth. Phys. Res. B 462, 24-31 (2020)
Radiobiology data of melanoma cells after low-energy neutron irradiation and boron compound administration. M Pedrosa-Rivera, MJ Ruiz-Magaña, P Álvarez, I Porras, J Praena, MP Sabariego, U Köster, M Haertlein, T Forsyth, JC Ramírez, C Jover, D Jimena, JL Osorio I Postuma, C Ruiz-Ruiz. Appl. Rad. Isot. 163:109205 (2020). doi: 10.1016/j.apradiso.2020.109205
Thermal neutron Relative Biological Effectiveness factors for Boron Neutron Capture Therapy from In Vitro Irradiations. M Pedrosa-Rivera, J Praena, I Porras, MP Sabariego, U Köster, Ml Haertlein, VT Forsyth, JC Ramírez, C Jover, D Jimena, JL Osorio, P Álvarez, C Ruiz-Ruiz, MJ Ruiz-Magaña. Cells 9, 2144 (2020). doi:10.3390/cells9102144
Polymer-Solvent Complexes and Intercalates POLYSOLVAT-12 Preface, JL Putaux, VT Forsyth, A Mader, Y Ogawa, S Prevost, R Schweins, Macromolecular Symposia 386 (1)
The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry. R Delhom, A Nelson, V Laux, M Haertlein, W Knecht, G. Fragneto, HP Wacklin-Knecht, Nanomaterials 10, 2439 (2020). https://doi.org/10.3390/nano10122439

2019

Complex transitions between dihydrate and anhydrate forms of ectoine - unexpected behaviour of a highly hygroscopic compatible solute in the solid state. WM Hutzler, E Mossou, R Vollrath, M Kohagen, I El Ghrissi, M Grininger, G Zaccai, J Smiatek, D Oesterhelt, CrystEng Comm (2019, in press). https://doi.org/10.1039/c9ce01599j
Molecular dynamics in cells: a neutron view. G. Zaccai, Biochem. Biophys. Acta 1864, 129475 (2020)
Hierarchical nanotube self-assembly of DNA minor groove binding ligand DB921 via alkali halide triggering, R Mizuta, T Narayanan, JM Devos, M Oliva, M Grey, J Webster, W-L Ling, A Round, D Munnur, E Mossou, A Farahat, D Boykin, WD Wilson, S Neidle, R Schweins, P Rannou, M Haertlein, VT Forsyth, EP Mitchell, Macromolecular Symposia 386,1800243 (2019). https://doi.org/10.1002/masy.201800243
BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring – recent advances and future perspectives, E Nji, DAK Traore, M Ndi, CA Jokog, DA Doyleh. Journal of Synchrotron Radiation 26, 1-8 (2019). https://doi.org/10.1107/S1600577519008981
Towards a molecular understanding of the water purification properties of Moringa seed proteins. M Moulin, E Mossou, L Signor, S Kieffer-Jaquinod, HM Kwaambwa, F Nermark, P Gutfreund, EP Mitchell, M Haertlein, VT Forsyth, AR Rennie, Journal of Colloid and Interface Science 554, 296-304 (2019). https://doi.org/10.1016/j.jcis.2019.06.071
Comparison of lipidic carrier systems for integral membrane proteins - MsbA as case study. D-M Kehlenbeck, I Josts, J Nitsche, S Busch, VT Forsyth, H Tidow. Biological Chemistry 400, 1509 (2019). https://doi.org/10.1515/hsz-2019-0171
In Vivo Water Dynamics in Shewanella oneidensis Bacteria at High Pressure. F Foglia, R Hazael, F Meersma, MC Wilding, V García Sakai, Sarah Rogers, LE Bove, MM Koza, M Moulin, M Haertlein, VT Forsyth, PF McMillan. Scientific Reports 9 (1), 8716 (2019). https://doi.org/10.1038/s41598-019-44704-3
Protein Short-Time Diffusion in a Naturally Crowded Environment, M Grimaldo, H Lopez, C Beck, F Roosen-Runge, M Moulin, JM Devos, V Laux, M Haertlein, S Da Vela, R Schweins, A Mariani, F Zgang, J-L Barray, M Oettel, VT Forsyth, T Seydel, F Schreiber, J. Phys. Chem. Lett. 10(8),1709-1715 (2019).DOI: 10.1021/acs.jpclett.9b00345 .
The production of matchout-deuterated cholesterol for the study of bilayer-cholesterol interactions, S Waldie, M Moulin, L Porcar, H Pichler, GA Strohmeier, M Skoda, VT Forsyth, M Haertlein, S Maric, M Cardenas, Scientific Reports 26;9(1):5118 (2019). DOI: 10.1038/s41598-019-41439-z.
A molecular mechanism for transthyretin amyloidogenesis, AW Yee, M Aldeghi, MP Blakeley, A Ostermann, P Mas, M Moulin, D de Sanctis, MW Bowler, C Mueller-Dieckmann, EP Mitchell, M Haertlein, B de Groot, E Boeri Erba, VT Forsyth, Nature Communications 10, 925 (2019). (https://doi.org/10.1038/s41467-019-08609-z). See summary.
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes. S Maric, T Kjellerup Lind, M Roman Raida, E Bengtsson,G Nordin Fredrikson, S Rogers, M Moulin,M Haertlein, VT Forsyth, M Wenk, T Günther Pomorski, T Arnebrant, R Lund and M Cárdenas, Scientific Reports 9:7591 (2019). https://doi.org/10.1038/s41598-019-43713-6

2018

Deuterium effects on human serum albumin in solution, J White, V Laux, N Fraser, D Heß, M Haertlein, VT Forsyth, Physica B: Condensed Matter, 551, 208-211 (2018). DOI: 10.1016/j.physb.2018.01.065
Neutron scattering for the study of biological systems-major opportunities within a rapidly changing landscape, VT Forsyth, P Moody, Acta Cryst. D 74, 1126-1128 (2018). DOI:10.1107/S2059798318017886
Structural basis for activation of plasma-membrane Ca 2+-ATPase by calmodulin, J Nitsche, I Josts, J Heidemann, HD Mertens, S Maric, M Moulin, M Haertlein, S Busch, VT Forsyth, DI Svergun, C Uetrecht, H Tidow, Communications Biology 1 (1), 206 (2018). DOI: 10.1038/s42003-018-0203-7
Conformational states of the ATP-binding cassette (ABC) transporter protein MsbA in lipid environment solution investigated by small-angle scattering using stealth carrier nanodiscs, I Josts, J Nitsche, S Maric, HD Mertens, M Moulin, M Haertlein, S Prevost, DI Svergun, S Busch, VT Forsyth, and H Tidow, Structure 26, 1072-1079 (2018). DOI: 10.1016/j.str.2018.05.
Solution structure of the cytochrome P450 reductase–cytochrome c complex determined by neutron scattering, SL Freeman, A Martel, JM Devos, J Basran, EL Raven, and GCK Roberts, J. Biol. Chem. 293, 5210-5219 (2018). doi: 10.1074/jbc.RA118.001941
The GAIIG domain from Amyloid-β and the HIV-1 gp120 V3 loop as a Source of Inspiration for Novel Amyloid Scaffolds and Potential Therapeutics, C. Kokotidoua, S. V. R. Jonnalagaddac, A. A. Orr, M. Seoane-Blanco, C.P. Apostolidou, M. J. van Raaij, M. Kotzabasakia, A. Chatzoudisa, E. Mossou, V. T. Forsyth, E. P. Mitchell, M. W. Bowler, A. L. Llamas-Saiz, P. Tamamis, A. Mitraki, FEBS Letters 592, 1777–1788 (2018). DOI.org/10.1002/1873-3468.13096
Perdeuteration of cholesterol for neutron scattering applications using recombinant Pichia pastoris, M Moulin, G Strohmeier, M Hirz, KC Thompson, AR Rennie, RA Campbell, H Pichler, S Maric, VT Forsyth, M Haertlein, Chemistry and Physics of Lipids 212, 80-87 (2018). doi.org/10.1016/j.chemphyslip.2018.01.006
Adsorption of Denatured Lysozyme at the Air−Water Interface: Structure and Morphology, RA Campbell, A Tummino, I Varga, OY Milyaeva, MM Krycki, S-Yow Lin, V Laux, M Haertlein, VT Forsyth, and BA Noskov, Langmuir 34 (17), 5020-5029. DOI:10.1021/acs.langmuir.8b00545
Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide. R Mizuta, JM Devos, J Webster, WL Ling, T Narayanan, A Round, D Munnur, E Mossou, AA Farahat, DW Boykin, WD Wilson, S Neidle, R Schweins, P Rannou, M Haertlein, VT Forsyth, EP Mitchell, Nanoscale 10, 5550–5558 (2018). DOI: 10.1039/C7NR03875E
Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine. S Waldie, TK Lind, K Browning, M Moulin, M Haertlein, VT Forsyth, A Luchini, GA Strohmeier, H Pichler, S Maric, M Cardenas, Langmuir 34 (1), 472-479. (2018). DOI: 10.1021/acs.langmuir.7b02716.
Effective interactions and dynamics of small passive particles in an active bacterial medium. EF Semeraro, JM Devos, T Narayanan, J. Chem. Phys. 148, 204905 (2018). doi.org/10.1063/1.5026778
The impact of deuteration on natural and synthetic lipids: A neutron diffraction study, A Luchini, R Delhom, B Demé, V Laux, M Moulin, M Haertlein, H Pichler, GA Strohmeier, H Wacklin, G Fragneto, Colloids and Surfaces B: Biointerfaces168, 126-133 (2018). DOI:10.1016/j.colsurfb.2018.02.009
Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function. S Rengachari, S Groiss, JM Devos, E Caron, E, N Grandvaux, D Panne, Proc. Natl. Acad. Sci. USA 115, E601-E609 (2018) . DOI: 10.1073/pnas.1718426115 (2018).

2017

Analysis of XFEL serial diffraction data from individual crystalline fibrils, Wojtas, D, Ayyer, K, Liang, MN, Mossou, E, Romoli, F, Seuring, C, Beyerlein, KR, Bean, RJ, Morgan, A, Oberthuer, D, Fleckenstein, H, Heymann, M, Gati, C, Yefanov, , Barthelmess, M, Ornithopoulou, E, Galli, L, Xavier, P, Ling, WL, Frank, M, Yoon, CH, White, TA, Bajt, S, Mitraki, A, Boutet, S, Aquila, A, Barty, Forsyth, VT, Chapman, H, Millane, RP, IUCrJ 4, 795-811 (2017). DOI: 10.1107/S2052252517014324
Back-exchange of deuterium in neutron crystallography: characterization by IR spectroscopy, Yee, AW; Blakeley, MP; Moulin, M; Haertlein, M; Mitchell, E; Forsyth, VT, J. Appl. Cryst 50, 660-664 (2017). DOI: 10.1107/S1600576717003624
In vivo analysis of the Escherichia coli ultrastructure by small-angle scattering, Semeraro, EF, Devos, JM; Porcar, L, Forsyth, VT; Narayanan, T, IUCrJ 4, 751-757 (2017). DOI: 10.1107/S2052252517013008
Effect of Phosphorylation on a Human-like Osteopontin Peptide, Lenton, Samuel; Grimaldo, Marco; Roosen-Runge, Felix; et al., Biophysical Journal 112, 1586-1596 (2017). DOI: 10.1016/j.bpj.2017.03.005
Laser processing of protein films as a method for accomplishment of cell patterning at the microscale, Prigipaki, A; Papanikolopoulou, K; Mossou, E; Mitchell, EP; Forsyth, VT; Selimis, A; Ranella, A; Mitraki, A., Biofabrication 9 (4), 045004 (2017). DOI: 10.1088/1758-5090/aa8859
Matchout deuterium labelling of proteins for small-angle neutron scattering studies using prokaryotic and eukaryotic expression systems and high cell-density cultures, Dunne, O; Weidenhaupt, M; Callow; Martel, A; Moulin, M; Perkins, SJ; Haertlein, M; Forsyth, VT, Eur. Biophys. J. 46, 425-432 (2017). DOI: 10.1007/s00249-016-1186-2
Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser, David Popp, N. Duane Loh, Habiba Zorgati, Umesh Ghoshdastider, Lu Ting Liow, Magdalena I. Ivanova, Mårten Larsson, Daniel P. DePonte, Richard Bean, Kenneth R. Beyerlein, Cornelius Gati, Dominik Oberthuer, David Arnlund, Gisela Brändén, Peter Berntsen, Duilio Cascio, Leonard M. G. Chavas, Joe P. J. Chen, Ke Ding, Holger Fleckenstein, Lars Gumprecht, Rajiv Harimoorthy, Estelle Mossou, Michael R. Sawaya, Aaron S. Brewster, Johan Hattne, Nicholas K. Sauter, Marvin Seibert, Carolin Seuring, Francesco Stellato, Thomas Tilp, David S. Eisenberg, Marc Messerschmidt, Garth J. Williams, Jason E. Koglin, Lee Makowski, Rick P. Millane, Trevor Forsyth, Sébastien Boutet, Thomas A. White, Anton Barty, Henry Chapman, Swaine L. Chen, Mengning Liang, Richard Neutze and Robert C. Robinson, Cytoskeleton (2017). 10.1002/cm.21378
Mobility of a Mononucleotide within a Lipid Matrix: A Neutron Scattering Study, Misuraca, Loreto; Natali, Francesca; da Silva, Laura; Peters, Judith; Deme, Bruno; Ollivier, Jacques; Seydel, Tilo; Laux-Lesourd, Valerie; Haertlein, Michael; Zaccai, Giuseppe; Deamer, David; Maurel, Marie Christine, Life 7 (1) (2017). DOI: 10.3390/life7010002
Self-Assembled Amyloid Peptides with Arg-Gly-Asp (RGD) Motifs As Scaffolds for Tissue Engineering, Deidda, G; Jonnalagadda, SVR; Spies, JW; Ranella, A; Mossou, E; Forsyth, VT; Mitchell, EP; Bowler, MW; Tamamis, P; Mitraki, A, ACS Biomaterials Science & Engineering 3 (7), 1404-1416 (2017). DOI: 10.1021/acsbiomaterials.6600570
Time-resolved neutron scattering provides new insight into protein substrate processing by a AAA plus unfoldase, Ibrahim, Z; Martel, A; Moulin, M; Kim, HS; Hartlein, M; Franzetti, B; Gabel, F., Scientific Reports 7, 40948 (2017). DOI: 10.1038/srep40948

2016

Direct visualisation of a Fe(IV)-OH intermediate in a heme enzyme, Kwon H, Basran J, Casadei CM, Fielding AJ, Schrader TE, Ostermann A, Devos JM, Aller P, Blakeley MP, Moody PCE, Raven EL (2016), Nature Communications 29;7:13445. doi: 10.1038/ncomms13445.
High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution, Howard, EI; Guillot, B; Blakeley, MP; Haertlein, M; Moulin, M; Mitschler, A; Cousido-Siah, A, Fadel, F; Valsecchi, WM; Tomizaki, T; Petrova, T; Claudot, J; Podjarny, A., IUCrJ 3, 115-126 (2016). DOI: 10.1107/S2052252515024161
Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2, Owen, GR; Channell, JA ; Forsyth, VT ; Haertlein, M ; Mitchell, EP ; Capovilla, A; Papathanasopoulos, M; Cerutti, NM, Biochemistry 55 (15), 2227-2237 (2016). DOI: 10.1021/acs.biochem.6b00154
Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses, Yee, AW; Moulin, M; Breteau, N; Haertlein, M; Mitchell, EP; Cooper, JB; Erba, EB ; Forsyth, VT, Angew. Chem. 55 (32), 9292-9296 (2016). DOI: 10.1002/anie.201602747
Investigation into the Relaxation Dynamics of Polymer-Protein Conjugates Reveals Surprising Role of Polymer Solvation on Inherent Protein Flexibility, Russo, D; Plazanet, M; Teixeira, J; Moulin, M; Hartlein, M; Wurm, FR; Steinbach, T, Biomacromolecules 17(1), 141-147 (2016). DOI: 10.1021/acs.biomac.5b01269
Macromolecular structure phasing by neutron anomalous diffraction, Cuypers, Maxime G; Mason, Sax A; Mossou, Estelle; Haertlein, Michael; Forsyth, V Trevor; Mitchell, Edward P, Scientific reports 6, 31487 (2016). DOI:10.1038/srep31487
Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation, Wacklin, HP; Bremec, BB; Moulin, M ; Rojko, N ; Haertlein, M ; Forsyth, VT ; Anderluh ; Norton, RS, Biohim. Biophys Acta 1858 (4), 640-652 (2016). DOI: 10.1016/j.bbamem.2015.12.019
Neutrons describe ectoine effects on water H-bonding and hydration around a soluble protein and a cell membrane, Zaccai, G; Bagyan, I; Combet, J; Cuello, GJ; Deme, B; Fichou, Y; Gallat, FX; Josa, VMG; von Gronau, S; Haertlein, M; Martel, A; Moulin, M; Neumann, M; Weik, M; Oesterhelt, D, Scientific Reports 6, 31434 (2016). DOI: 10.1038/srep31434
SAXS/SANS on Supercharged Proteins Reveals Residue-Specific Modifications of the Hydration Shell, Kim, HS; Martel, A; Girard, E; Moulin, M; Hartlein, M; Madern, D; Blackledge, M; Franzetti, B; Gabel, F, Biophys J. 110 (10), 2185-2194 (2016). DOI: 10.1016/j.bpj.2016.04.013
SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering, Jordan, A; Jacques, M; Merrick, C; Devos, J; Forsyth, VT; Porcar, L; Martel, A, J. Appl. Cryst 49 (6), 2015-2020 (2016). DOI: 10.1107/S1600576716016514
Self-assembly Controls Self-cleavage of HHR from ASBVd (-): a Combined SANS and Modeling Study, Leclerc, Fabrice; Zaccai, Giuseppe; Vergne, Jacques; Rihova, Martina; Martel, Anne; Maurel, Marie-Christine, Scientific Reports 6 30287 (2016). DOI:10.1038/srep30287
Structural studies of hydrated samples of amorphous calcium phosphate and phosphoprotein nanoclusters, Lenton, S; Nylander, T ; Holt, C; Sawyer, L ; Hartlein, M ; Muller, H ; Teixeira, S, Eur. Biophys. J. 45 (5), 405-412 (2016). DOI: 10.1007/s00249-015-1109-7
Structure of the H-NS-DNA nucleoprotein complex. van der Maarel, JRC; Guttula, D; Arluison, V; Egelhaaf, SU ; Grillo, I ; Forsyth, VT, Soft Matter 12 (15), 3636-3642 (2016). DOI: 10.1039/c5sm03076e
Water Collective Dynamics in Whole Photosynthetic Green Algae as Affected by Protein Single Mutation. Russo, D ; Rea, G ; Lambreva, MD ; Haertlein, M ; Moulin, M ; De Francesco, A ; Campi, G., J. Phys. Chem. Lett 7 (13), 2429-2433 (2016). DOI: 10.1021/acs.jpclett.6b00949
Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering. Foglia, F ; Hazael, R; Simeoni, GG ; Appavou, MS ; Moulin, M; Haertlein, M ; Forsyth, VT ; Seydel, T; Daniel, I ; Meersman, F , McMillan, PF, Scientific Reports 6, 18862 (2016). DOI: 10.1038/srep18862
Biomolecular Deuteration for Neutron Structural Biology and Dynamics, Haertlein, M, Moulin M, Devos J, Laux V, Dunne O, Forsyth VT, Methods in Enzymology 566, 113-157 (2016). doi: 10.1016/bs.mie.2015.11.001
Applications of Synchrotron and Neutron Radiation, Brennich M, Cardenas M, Castillo-Michel H, Cotte M, Forsyth VT, Haertlein M, Kimber S, Le Duc G, Mitchell EP, Round A, Salome M, Sztucki M, Nanoparticle Characterisation Methods: in Pharmaceutical Nanotechnology: Innovation and Production, Eds Cornier J, Kwade A, Owen A, Van de Voorde M (Wiley) (2016). DOI: 10.1002/9783527800681.ch8

2015

Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation, Wacklin, H.,P., Bremec, B.B., Moulin, M., Rojko, N., Haertlein, M., Forsyth, V.T., Anderluh, G., Norton, R.S., Biochimica et Biophysica Acta - Biomembranes (2015, in press).
High resolution neutron and X-ray diffraction RT studies of an H-FABP-Oleic acid complex: study of the internal water cluster and the ligand binding by a transferred multipolar electron density distribution, Podjarny AD, Howard EI, Guillot B, Blakeley M, Haertlein M, Moulin M, Mitschler A, Cousido-Siah A, Fadel F, Valsecchi W, Tomizaki T, Tatiana Petrova T and Claudot J, IUCrJ in press
Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering, Fabrizia F, Hazael R, Simeoni GG, Appavou M-S, Moulin M, Haertlein M, Forsyth VT, Seydel T, Daniel I, Meersman F,& McMillan PF,Sci Rep. in press
Biomolecular Deuteration for Neutron Structural Biology and Dynamics Methods in Enzymology, Haertlein M, Moulin M, Devos JM, Laux V, Dunne O, Forsyth, VT, in press
Diffraction evidence for the structure of cellulose microfibrils in bamboo, a model for grass and cereal celluloses. Lynne H. Thomas, V. Trevor Forsyth, Anne Martel, Isabelle Grillo, Clemens M. Altaner and Michael C. Jarvis,, BMC Plant Biology 15, 153 (2015) [Open access]
Light Emitting Self-Assembled Peptide Nucleic Acids Exhibit Both Stacking and Watson-Crick Base-Pairing, Berger, O., Adler-Abramovich, L., Levy-Sakin, M., Grunwald, A., Liebes-Peer, Bachar, M., Buzhansky, L., Mossou, E., Forsyth, V.T., Schwartz, T., Ebenstein, Y., Frolow, F., Shimon, L.J.W., Patolsky, F., Gazit, E., Nature Nanotechnology 10, 353-360 (2015).
A review of the biology of calcium phosphate sequestration with special reference to milk, Lenton, S., Nylander, T., Teixeira, S., Holt, C., Dairy Sci Technol. 95: 3–14 (2015).
The pentaplasmic nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins, Edlich-Muth, C., Artero, J.-B., Callow, P., Przewloka, M.R., Watson, A.A., Zhang, W., Glover, D.M., Debski, J., Dadlez, M., Round, A.R., Forsyth, V.T., Laue, E.D., J. Mol. Biol. 427 (10), 1949-63 (2015).
Formation and Characterization of Supported Lipid Bilayers Composed of Hydrogenated and Deuterated Escherichia coli Lipids, Lind TK, Wacklin H, Schiller J, Moulin M, Haertlein M, Pomorski TG, Cárdenas M (2015), PLoS One 10(12):e0144671.
Investigation into the relaxation dynamics of polymer-protein conjugates reveals surprising role of polymer solvation on inherent protein flexibility. Russo D, Plazanet M, Teixeira J, Moulin M, Härtlein M, Wurm FR, Steinbach T.(2015), Biomacromolecules 2015 Nov 16. [Epub ahead of print]
Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase. Raasakka A, Myllykoski M, Laulumaa S, Lehtimäki M, Härtlein M, Moulin M, Kursula I, Kursula P.(2015), Sci Rep. 5:16520
Production, crystallization and neutron diffraction of fully deuterated human myelin peripheral membrane protein P2. Laulumaa S, Blakeley MP, Raasakka A, Moulin M, Härtlein M, Kursula P.(2015), Acta Crystallogr F Struct Biol Commun. 71(Pt 11):1391-5.
Dynamic footprint of sequestration in the molecular fluctuations of osteopontin. Lenton S, Seydel T, Nylander T, Holt C, Härtlein M, Teixeira S, Zaccai G.(2015), J R Soc Interface, 12(110):0506.
Grafted biomembranes containing membrane proteins - the case of the leucine transporter. Jagalski V, Barker RD, Thygesen MB, Gotfryd K, Krüger MB, Shi L, Maric S, Bovet N, Moulin M, Haertlein M, Günther Pomorski T, Loland CJ, Cárdenas M.(2015), Soft Matter, 11(39):7707-11.
Lipid polyunsaturation determines the extent of membrane structural changes induced by Amphotericin B in Pichia pastoris yeast.de Ghellinck A, Fragneto G, Laux V, Haertlein M, Jouhet J, Sferrazza M, Wacklin H.(2015), Biochim Biophys Acta, 1848(10 Pt A):2317-25.
The aggregation of "native" human serum albumin. White J, Heß D, Raynes J, Laux V, Haertlein M, Forsyth T, Jeyasingham A.(2015), Eur Biophys J., 44(5):367-71.
Adaptation of Extremophilic Proteins with Temperature and Pressure: Evidence from Initiation Factor 6, Calligari PA, Calandrini V, Ollivier J, Artero JB, J Phys Chem B, 119(25):7860-73. Härtlein M, Johnson M, Kneller GR (2015)
Hydration water mobility is enhanced around tau amyloid fibers. Fichou Y, Schirò G, Gallat FX, Laguri C, Moulin M, Combet J, Zamponi M, Härtlein M, Picart C, Mossou E, Lortat-Jacob H, Colletier JP, Tobias DJ, Weik M. (2015), Proc Natl Acad Sci U S A, 112(20):6365-70
Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins. Schirò G, Fichou Y, Gallat FX, Wood K, Gabel F, Moulin M, Härtlein M, Heyden M, Colletier JP, Orecchini A, Paciaroni A, Wuttke J, Tobias DJ, Weik M.(2015), Nat Commun.,6:6490.
Vibrational dynamics changes of protein hydration water across the dynamic transition. Paciaroni A, Orecchin A, Sebastiani F, Capaccioli S, Ngai K L, Moulin M, Haertlein M, Petrillo C and a, Sacchetti F (2015), J. Non-Cryst. Solids 407, 465–471
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli. Maric S, Thygesen MB, Schiller J, Marek M, Moulin M, Haertlein M, Forsyth VT, Bogdanov M, Dowhan W, Arleth L, Pomorski TG, (2015), Appl Microbiol Biotechnol. 99(1):241-54.

2014

Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein, Melina Haupt, Matthew P. Blakeley, Stuart J. Fisher, Sax Mason, Jon B. Cooper, Edward. P. Mitchell, V. Trevor Forsyth, IUCrJ Biology & Medicine (2014, in press).
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli. Selma Maric, Mikkel B. Thygesen, Jürgen Schiller, Magdalena Marek, Martine Moulin, Michael Haertlein, V. Trevor Forsyth, Mikhail Bogdanov, William Dowhan, Lise Arleth, Thomas Günther Pomorski, , Biochem. Biophys. Acta (2014, in press).
Combining X-ray and neutron crystallography with molecular simulation to study binding, isomerization, and epimerization of L-arabinose catalyzed by D-xylose isomerase, Langan, P., Sangha, A.K., Wymore, T., Parks, J.M., Yang, Z.K., Hanson, B.L., Fisher, Z., Mason, S. A., Blakeley, M.P., Forsyth, V.T., Glusker, J.P., Carrell, H. L., Smith, J.C., Keen, D.A., Graham, D.E., Kovalevsky, A., Structure 22 (9), 1287-1300 (2014).
Intrinsic disorder within the erythrocyte binding-like proteins from Plasmodium falciparum, M. Blanc, T. L. Coetzer, M. Blackledge, M. Haertlein, E. P. Mitchell, V. T. Forsyth, M. R. Jensen, Biochemica Biophysica Acta - Proteins and Proteomics (accepted subject to revision)
SPINE-compatible ‘carboloops’: a new microshaped vitreous carbon sample mount for X-ray and neutron crystallography. Romoli, F., Mossou, E., Cuypers, M., van der Linden, P., Carpentier, P., Mason, S.A., Forsyth, V.T. & McSweeney, S., Acta Cryst. F70 (5), 681-4 (2014).
Production and analysis of perdeuterated lipids from Pichia pastoris cells. De Ghellinck, A., Schaller, H., Laux, V., Haertlein, M., Sferrazza, M., Maréchal, E., Wacklin, H., et al. PloS one, 9(4), e92999. (2014).
A review of the biology of calcium phosphate sequestration with special reference to milk. Lenton, S., Nylander, T., Teixeira, S., Holt, C. Dairy Science and Technology. In Press.`
Interfacial Structure of Immobilized Antibodies and Perdeuterated HSA Measured with Neutron Reflectivity. Benjamin J. Cowsill, Xiubo Zhao, Thomas A. Waigh, Saji Eapen, Robert Davies, Valerie Laux, Michael Haertlein, V. Trevor Forsyth, Jian R. Lu. Langmuir (2014, in press)
Crystal structure of the self-assembling zwitterionic form of L-phenylalanine at neutral pH, Estelle Mossou, Susana C. M. Teixeira, Edward P. Mitchell, Sax A. Mason, Lihi Adler-Abramovich, Ehud Gazit and V. Trevor Forsyth. Acta Cryst. C (2014, in press)
Stealth carriers for low-resolution structure determination of membrane proteins in solution, Maric, S., Skar-Gislinge, N., Roi Midtgaard, S., Thygesen, M.-B., Schiller, J., Frielinghaus, H., Moulin, M., Haertlein, M., Forsyth, V.T., Günther-Pomorski, T., Arleth, L., Acta Cryst. D, 70, 317-328 (2014)
Self-Assembly of an Aspartate-Rich Sequence from the Adenovirus Fibre Shaft: Insights from Molecular Dynamics Simulations and Experiments. Tamamis, P., Terzaki, K., Kassinopoulos, M., Mastrogiannis, L., Mossou, E., Forsyth, V.T., Mitchell, E.P., Mitraki, A., Archontis, G., J. Phys. Chem. (2014, in press) DOI: 10.1021/jp409988n
Mineralisation of soft and hard tissues and the stability of biofluids. Holt, C., Lenton, S., Nylander, T., Sørensen, E.S., Teixeira, S. Journal of Structural Biology, 185(3), 383-396 (2014)

2013

Neutron reflectometry elucidates density profiles of deuterated proteins adsorbed onto surfaces displaying poly(ethylene glycol) brushes: evidence for primary adsorption.Schneck E, Schollier A, Halperin A, Moulin M, Haertlein M, Sferrazza M, Fragneto G.Langmuir. 2013 Nov 19;29(46):14178-87. doi: 10.1021/la403355r.
A neutron reflection study of adsorbed deuterated myoglobin layers on hydrophobic surfaces.Brouette N, Fragneto G, Cousin F, Moulin M, Haertlein M, Sferrazza M.J Colloid Interface Sci. 2013 Jan 15;390(1):114-20. doi: 10.1016/j.jcis.2012.09.040.
Protein surface and core dynamics show concerted hydration-dependent activation.Wood K, Gallat FX, Otten R, van Heel AJ, Lethier M, van Eijck L, Moulin M, Haertlein M, Weik M, Mulder FA.Angew Chem Int Ed Engl. 2013 Jan 7;52(2):665-8. doi: 10.1002/anie.201205898.
Small angle neutron scattering for the study of solubilised membrane proteins. Breyton C, Gabel F, Lethier M, Flayhan A, Durand G, Jault JM, Juillan-Binard C, Imbert L, Moulin M, Ravaud S, Härtlein M, Ebel C. Eur Phys J E Soft Matter. 2013 Jul;36(7):71. doi: 10.1140/epje/i2013-13071-6.
Mineralized self-assembled peptides on 3D laser-made scaffolds: a new route toward “scaffold on scaffold” hard tissue engineering, Terzaki, K., Kalloudi, E., Mossou, E., Mitchell, E. P., Forsyth, V. T., Rosseeva, E., Simon, P., et al. Biofabrication, 5(4), 045002 (2013).
Adsorption of a-synuclein to supported lipid bilayers– positioning and role of electrostatics Hellstrand, E. Grey, M. Ainalem, M.-L., Ankner, J., Forsyth, V. T., Fragneto, G., Haertlein, M., Dauvergne, M.-T., Nilsson, H., Brundin, P., Linse, S., Nylander, T., Sparr, E., ACS Chemical Neuroscience., 4, 1339-1351 (2013)
Structure and dynamics of a complex of cellulose with EDA: insights into the action of amines on cellulose D. Sawada, Y. Nishiyama, L. Petridis, R. Parthasarathi, S. Gnanakaran, V. T. Forsyth, M. Wada, P. Langan, Cellulose, 20, 1563-1571 (2013)
Structure of cellulose microfibrils in primary cell-walls from collenchyma. L.H. Thomas, V.T. Forsyth, A. Šturcová, C.J. Kennedy, R.P. May, C.M. Altaner, D.C. Apperley, T.J. Wessand M.C. Jarvis, Plant Physiology, 161, 465-476 (2013)
Near-atomic resolution neutron crystallography on perdeuterated Pyrococcus furiosus rubredoxin implicates hydronium ions and protonation state equilibria in redox changes, M.G. Cuypers, S.A. Mason, M. P. Blakeley, E.P. Mitchell, M. Haertlein, and V. T. Forsyth, Angewandte Chemie, 52 (2013) 1022-25 (DOI: 10.1002/ange.201207071)
Solution Conformations of Early Intermediates in Mos1 Transposition, M. Cuypers, M. Trubitsyna, P. Callow, V. Forsyth, J. Richardson, <abbr title="Nucleic Acids Research">Nucl. Acids Res.</abbr> (2013) 41 (3), 2020-2033. (DOI: 10.1093/nar/gks1295)

2012

Structure of cellulose microfibrils in primary cell-walls from collenchyma ,L.H. Thomas, V.T. Forsyth, A. Sturcova, C.J. Kennedy, R.P. May, C.M. Altaner, D.C Apperley, T.J. Wess, M.C. Jarvis, Plant Physiol (2012) in press.
Aggregation Behaviour of Bovine Kappa- and Beta- Casein Studied with Small Angle Neutron Scattering and Crogenic Transmission Electron Microscopy , S. Ossowski, A. Jackson, M. Obiols-Rabasa, C. Holt, S. Lenton, L. Porcar, M. Paulsson, T. Nylander, Langmuir 28 (38), 13577-89 (2012).
A Joint X-ray/Neutron Structure of D-xylose Isomerase with Sorbitol: Atomic Details of Polyol Inhibitor Binding , A.Y. Kovalevsky, L. Hanson, S.A. Mason, V.T.Forsyth, S.Z. Fisher, M. Mustyakimov, D.A. Keen, P. Langan, Acta Cryst D (2012) in press.
Structure and operation of the DNA-translocating Type I DNA restriction enzymes. C.K. Kennaway, J.E. Taylor, C.F. Song, W. Potrzebowski, W. Nicholson, J.H. White, A. Swiderska, A. Obarska-Kosinska, P. Callow, L.P. Cooper, G.A. Roberts, J.-B. Artero, J.M. Bujnicki, J. Trinick, G. Kneale, D.T.F. Dryden, Genes & Development (2012) 26, 92-104D.
Water in crystalline fibers of dihydrate beta-chitin results in unexpected absence of intramolecular hydrogen bonding , D.Sawada, Y. Nishiyama, P. Langan, V.T. Forsyth, S. Kimura, M. Wada, PLoS ONE 7 (6), e39376 (2012).
Dynamical Coupling of Intrinsically Disordered Proteins and Their Hydration Water: Comparison with Folded Soluble and Membrane Proteins , F.-X. Gallat, A. Laganowsky, K. Wood, F. Gabel, L. van Eijck, J. Wuttke, M. Moulin, M. Haertlein, D. Eisenberg, J.-P. Colletier, G. Zaccai and M. Weik. Biophysical Journal (2012) Vol. 103, 129–136.
Structural and Functional Analysis of the Symmetrical Type I Restriction Endonuclease R.EcoR124INT. J.E. Taylor, A. Swiderska, J.-B. Artero, P. Callow, G. Kneal, PLoS ONE 7 (2012) (4) e35263.
Collective Dynamics of Intracellular Water in Living Cells, A. Orecchini, F. Sebastiani, M. Jasnin, A. Paciaroni, A. De Francesco, C. Petrillo, M. Moulin, M. Haertlein, G. Zaccai, F. Sacchetti, J. Phys.: Conf. Ser. 340, 012091.
The rheological and structural properties of Fmoc peptide based hydrogels: The effect of aromatic molecular architecture on self-assembly and physical characteristics, E. Gazit, R. Orbach, I. Mironi-Harpaz, L. Adler-Abramovich, E. Mossou, E.P. Mitchell, V.T. Forsyth, D. Seliktar, Langmuir (2012) Jan 31; 28(4), 2015-2022.
Direct Determination of the Hydrogen Bonding Arrangement in Anhydrous β-chitin by Neutron Fiber Diffraction, D. Sawada, Y. Nishiyama, P. Langan, V.T. Forsyth, S. Kimura, M. Wada, Biomacromolecules (2012) 13(1), 288-291.

2011

Structure and operation of the DNA-translocating Type I DNA restriction enzymes. C.K. Kennaway, J.E. Taylor, C.F. Song, W. Potrzebowski, W. Nicholson, J.H. White, A. Swiderska, A. Obarska-Kosinska, P. Callow, L.P. Cooper, G.A. Roberts, J.-B. Artero, J.M. Bujnicki, J. Trinick, G. Kneale, D.T.F. Dryden, <abbr title="Genes & Development">Genes & Dev.</abbr> (2012) 26, 92-104.
Dynamical properties of the hydration shell of fully deuterated myoglobin, K. Achterhold, A. Ostermann, M. Moulin, M Haertlein, T Unruh and Fritz G. Parak, Phys. Rev. (2011) E 84, 041930
Preliminary neutron crystallographic study of human transthyretin, M. Haupt, M. Blakeley, S. Teixeira, S. Mason, E. Mitchell, J. Cooper and V.T. Forsyth, Acta Crystallographica (2011) F67, 1428–1431.
Nanostructure of cellulose microfibrils in spruce wood, A.N. Fernandes, L.M. Thomas, C.M. Altaner, P. Callow, V.T. Forsyth, D.C. Apperley, C.J. Kennedy & M.C. Jarvis, Proc. Natl. Acad. Sci. USA. (2011) 108 (47), 1195-1203.
Direct Determination of the Base-Pair Force Constant of DNA from the Acoustic Phonon Dispersion of the Double Helix, L. Van Eijck, L., Merzel, F., Rols, S., Olivier, J., Forsyth, V.T., Johnson, M.R., Direct Phys. Rev. Lett. (2011) 107, 088102. [Highlight in Nature 477, 372 (2011)].
The elusive hydronium ion is found in an enzyme exchanging role with a proton at lower pH, A. Y. Kovalevsky, B. L. Hanson, S. A. Mason, T. Yoshida, S. Z. Fisher, M. Mustyakimov, V. T. Forsyth, M. P. Blakeley, D. A. Keen, P. Langan, Angewandte Chemie 50, 7520-7523 (2011). DOI: 10.1002/anie.201101753
Inducing phase changes in crystals of macromolecules: status and perspectives for controlled crystal dehydration. S. Russi, D. H. Juers, J. Sanchez-Weatherby, E. Pellegrini, E. Mossou, V. T. Forsyth, J. Huet, A. Gobbo, F. Felisaz, R. Moya, S. McSweeney, S. Cusack, F. Cipriani, M. W. Bowler, Journal of Structural Biology 175 (2), 236-243 (2011).
Neutron crystallographic and molecular dynamics studies of the structure of ammonia-cellulose I: rearrangement of hydrogen bonding during the treatment of cellulose with ammonia, S. Wada, Y. Nishiyama, G. Bellesia, V.T. Forsyth, S. Gnanakaran, P. Langan, Cellulose (2011) 18,191-206.
Neutron fibre diffraction studies of amyloid using H2O/D2O isotopic replacement, S.M. Tiggelaar, E. Mossou, P. Callow, S. Callow, S.C.M. Teixeira, E.P. Mitchell, A. Mitraki, V.T. Forsyth, Acta Crystallographica (2011) F67, 332–335.
Variation in the organisation and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly, S. Vijayakrishnan, P. Callow, M. A. Nutley, D. P. McGow, D. Gilbert, P. Kropholler, A. Cooper, O. Byron and J. G. Lindsay, Biochem J. (2011) 437(3), 565-574.
Bilayer-mediated clustering and functional interaction of MscL channels. S.L. Grage, A.M. Keleshian, T. Turdzeladze, A.R. Battle, W.C. Tay, R.P. May, S.A. Holt, S.A. Contera, M. Haertlein, M. Moulin, P. Pal, P.R. Rohde, V.T. Forsyth, A. Watts, K.C. Huang, A.S. Ulrich, B. Martinac, Biophys J. (2011) 100(5),1252-60.
Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface. Howard EI, Blakeley MP, Haertlein M, Haertlein IP, Mitschler A, Fisher SJ, Siah AC, Salvay AG, Popov A, Dieckmann CM, Petrova T, Podjarny A. J Mol Recognit. (2011) 24(4), 724-32.
Asparaginyl-tRNA synthetase pre-transfer editing assay. Danel F, Caspers P, Nuoffer C, Härtlein M, Kron MA, Page MG. Curr Drug Discov Technol. 2011 Mar 1;8(1):66-75.
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings. N. Rochel, F. Ciesielski, J. Godet, E. Moman, M. Roessle, C. Peluso-Iltis,M. Moulin, M. Haertlein, P. Callow, Y. Mély, D.I. Svergun, D. Moras, Nature Structural & Molecular Biology (2011) 18, 564–570.
A hybrid structural model of the complete Brugia malayi cytoplasmic asparaginyl-tRNA synthetase, Crepin, T., Peterson, F., Haertlein, M., Jensen, D, Wang, C., Cusack, S.and Kron, M; J. Mol. Biol. (2011) 405(4), 1056-69.

2010

Nanostructure of the "protein-nanoparticle corona" an indicator of toxicity?, J.W. White, J-M. Lin, ; C.J. Ang, R.A. Campbell, V. Laux, M. Haertlein, G. Fragneto, 2010 International Conference on Nanoscience and Nanotechnology (ICONN), 2010 International Conference on, (2010) 289 - 292
Crystallization and preliminary X-ray diffraction analysis of human cytosolic seryl-tRNA synthetase, J.B. Artero, S.C.M. Teixeira, E.P. Mitchell, M.A. Kron, V.T. Forsyth, Michael Haertlein, Acta Cryst. F. (2010) 66 (11) 1521-1524.
News: Cosmos Magazine : The structure of sweetness, S.C.M. Teixeira, 9 th nov. 2010.
Sweet neutron crystallography, Teixeira, S.C.M., Blakeley, M.P., Leal, R.M.F., Gillespie, S.M., Mitchell, E.P., Forsyth, V.T., Acta Cryst. D (2010) 66 (11), 1139-1143.
Using neutron protein crystallography to understand enzyme mechanism, J. Glusker, A. Kovalevsky, L. Hanson, Z. Fisher, M. Mustkakimov, S.A Mason, V.T. Forsyth, P. Langan, Acta Cryst. D (in press).
Combined neutron and X-ray diffraction studies of DNA in crystals and solutions, Leal, R.M.F., Callow, S., Callow, P., Blakeley, M.P., Cardin, C.J., Denny, W.A., Teixeira, S.C.M., Mitchell, E.P., Forsyth, V.T. Acta Cryst. D (2010), 66 (11), 1244-1248.
Neutron Macromolecular crystallography with LADI-III, M.P. Blakeley, S.C.M. Teixeira, Isabelle Petit-Haertlein, I. Hazemann, Andre Mitschler, M. Haertlein, E. Howard, A.D. Podjarny, Acta Cryst. D, (2010) 66 (11), 1198-1205.
Effect of crowding on the conformation of interwound DNA strands from neutron scattering measurements and Monte Carlo simulations, Xiaoying Zhu, Siow Yee Ng, Amar Nath Gupta, Yuan Ping Feng, Bow Ho, Alain Lapp, Stefan U. Egelhaaf, V. Trevor Forsyth, Michael Haertlein, Martine Moulin, Ralf Schweins, and Johan R. C. van der Maarel, Phys. Rev. (2010) E 81, 061905
Looking at hydrogen bonds with cellulose, Nishiyama, Y., Langan, P., Wada, M., Forsyth, V.T., Acta Cryst. D (2010) 66 (11), 1172-1177.
Structural and Functional Analysis of the Engineered Type I DNA Methyltransferase EcoR124INT, Taylor, J. E., Callow, P., Swiderska, A. & Kneale, G. G. Journal of Molecular Biology (2010) 398, 391-399.
Structural Insights into Substrate Specificity and the anti Beta-Elimination Mechanism of Pectate Lyase, A. Seyedarabi, T.-T. To, S. Ali, S. Hussain, M. Fries, R. Madsen, M.H. Clausen, S. Teixeira, K. Brocklehurst, R.W. Pickersgill, Biochemistry (2010) 49 (3), 539-546
Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies, I. Petit-Haertlein, M. P. Blakeley, E. Howard, I. Hazemann, A. Mitschler, A. Podjarny and M. Haertlein, Acta Crystallogr Sect F Struct Biol Cryst Commun. (2010) 66(Pt 6), 665-9
Investigation of gammaE-crystallin target protein binding to bovine lens alpha-crystallin by small-angle neutron scattering. Clarke MJ, Artero JB, Moulin M, Callow P, Carver JA, Griffiths PC, Haertlein M, Harding JJ, Meek KM, Timmins P, Regini JW. Biochim Biophys Acta. (2010) 1800(3):392-7.
Metal Ion Roles and the Movement of Hydrogen during the Reaction Catalyzed by D-Xylose Isomerase, A.Y. Kovalevsky, L. Hanson, S.Z. Fisher, M. Mustyakimov, S. Mason, V.T. Forsyth, M.P. Blakeley, D. Keen, T. Wagner, H.L. Carrell, A.K. Katz, J.P. Glusker, P. Langan, Structure (2010) 18 (6), 688-699.
Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly, Vijayakrishnan S, Kelly SM, Gilbert RJ, Callow P, Bhella D, Forsyth T, Lindsay JG, Byron O., J Mol Biol. (2010) 399(1):71-93.

2009

Investigation of <gamma>E-Crystallin Target Protein Binding to Bovine Lens Alpha-Crystallin by Small-Angle Neutron Scattering. M.J. Clarke, J.B. Artero, M.J. Moulin, P. Callow, J.A. Carver, P.C. Griffiths, M. Haertlein, J.J. Harding, K.M. Meek, P. Timmins, J. Regini, Biochimica et Biophysica Acta (2009).
Coupled relaxations at the protein-water interface in the picosecond time scale, Paciaroni A, Cornicchi E, Marconi M, Orecchini A, Petrillo C, Haertlein M, Moulin M, Sacchetti F. J. R. Soc. Interface (2009) 6, 635-640.
Deciphering Membrane Insertion of the Diphtheria Toxin T Domain by Specular Neutron Reflectometry and Solid-State NMR Spectroscopy, Chenal A, Prongidi-Fix L, Perier A, Aisenbrey C, Vernier G, Lambotte S, Haertlein M, Dauvergne M-T, Fragneto G, Bechinger B, Gillet D, Forge V, Ferrand M, J. Mol. Biol. (2009) 391, 872–883 (corrected authors list, see erratum).
The Double Super Helix model of high density lipoprotein, Wu Z, Gogonea V, Lee X, Wagner MA, Li XM, Huang Y, Undurti A, May RP, Haertlein M, Moulin M, Gutsche I, Zaccai G, Didonato JA, Hazen SL. (2009) J. Biol. Chem. (2009) 284(52):36605-19.
A preliminary neutron crystallographic study of an A-DNA crystal, Leal, R.M.F, Teixeira, S.C.M., Blakeley, M., Mitchell, E.P., Forsyth, V.T., Acta Cryst (2009) F65, 232-235.
Design of metal-binding sites onto self-assembled peptide fibrils, Kasotakis, E., Mossou, E., Adler-Abramovich, L., Mitchell, E.P., Forsyth, V.T., Gazit, E., Mitraki, A., Biopolymers (2009) 92(3): 164-172.
Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein, Isabelle Petit-Haertlein, Matthew P. Blakeley, Eduardo Howard, Isabelle Hazemann, Andre Mitschler, Michael Haertlein and Alberto Podjarny, Acta Cryst. (2009). F65, 406–409.
Neutron macromolecular crystallography. Blakeley M.P., Crystallography Reviews (2009) 15, 157-218.

2008

Fingerprints of Amorphous Icelike Behavior in the Vibrational Density of States of Protein Hydration Water. A. Paciaroni, A. Orecchini, E. Cornicchi, M. Marconi, C. Petrillo, M. Haertlein, M. Moulin, H. Schober, M. Tarek, and F. Sacchetti., (2008) Phys. Rev. Lett.101, 148104
Neutron crystallography: opportunities, challenges, and limitations. Blakeley M.P., Langan P., Niimura N., Podjarny A., (2008) Curr. Opin. Struct. Biol. 18(5):593-600
Neutron Crystallography, Molecular Dynamics, and Quantum Mechanics Studies of the Nature of Hydrogen Bonding in Cellulose Iβ. Nishiyama,Y., Johnson,G.P., French, A.D., Forsyth, V.T., Langan, P., (2008) Biomacromolecules 9 (11), 3133–3140.
Coupled thermal fluctuations of proteins and protein hydration water on the picosecond timescale. A. Paciaroni; A. Orecchini; E. Cornicchi; M. Marconi; C. Petrillo; M. Haertlein; M. Moulin; F. Sacchetti. Philosophical Magazine, Volume 88, Issue 33, First published 2008, Pages 4071–4077
Absorption correction based on a 3D model reconstruction from visual images, Leal, R., Teixeira, S., Rey, V., Forsyth, V.T., Mitchell, E., (2008) J. Appl. Cryst. 41, 729-737.
Matchout deuterium labelling of proteins for low resolution neutron scattering studies of biological macromolecules, P. Callow, J.-B. Artero, M. Weidenhaupt, M. Smolle, O. Byron, J. G. Lindsay, S.C.M. Teixeira, M. Moulin, M. Haertlein, V.T. Forsyth, E. Biophys. J. (in preparation).
Force-induced structural transitions in cross-linked DNA films, Andre, A., Fontaine-Vive, F., Forsyth, V. T., Maoller, H., Fischer, T., Maret, G. and Gisler, T. (2008)Eur. Biophys. J. 37 (6) 749-757.
Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering, Laux, V., Callow, P., Svergun, D.I., Timmins, P.A., Forsyth, V.T., Haertlein, M., (2008) Eur Biophys J. 37 (6), 815-822
HsdR Subunit of the Type I Restriction-Modification Enzyme EcoR124I: Biophysical Characterisation and Structural Modelling, A. Obarska-Kosinska1, J.E. Taylor, P. Callow, J. Orlowski, J.M. Bujnicki, G.Kneale, (2008) J. Mol. Biol. 376, 438-452.
Selective deuterium labelling of DNA polymers, I. Parrot, M. Haertlein, V.T. Forsyth, Eur. Biophys. J. (2008) 37 (6), 815-822
New sources and instrumentation for neutrons in biology, S.C.M. Teixeira, J.F. Ankner, M.C. Bellissant-Funel, R. Bewley, M.P. Blakeley, P. Callow, L. Coates, R. Dahint, R. Dagliesh, N. Dencher, J. Dhont, P. Fischer, T. Forsyth, G. Fragneto, B. Frick, J. Geue, R. Gilles, T. Gutberlet, M. Haertlein, T. Hauss, W. Häussler, W.T. Heller, K. Herwig, O. Holderer, F. Juranyi, R. Kampmann, R. Knott, J. Kohlbrecher, S. Kreuger, P. Langan, R. Lechner, G. Lynn, C. Majkrzak, R. May, F. Meilleur, Y. Mo, K. Mortensen, D.A.A. Myles, F. Natali, C. Neylon, N. Niimura, J. Ollivier, A. Ostermann, J. Peters, J. Pieper, A. Rühm, D. Schwahn, K. Shibata, A.K. Soper, T. Straessle, U.-i. Suzuki, I. Tanaka, M. Tehei, P. Timmins, N. Torikai, T. Unruh, V. Urban, R. Vavrin, K. Weiss, G. Zaccai, Chem. Phys.(2008) 345, 133-151.
In vivo measurement of internal and global macromolecular motions in E. coli, Jasnin M, Moulin M, Haertlein M, Zaccai G, Tehei M, (2008). Biophys J. 95(2), 857-864
Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase, M.P. Blakeley, F.Ruiz, R. Cachau, I. Hazemann, F. Meilleur, A. Mitschler, S. Ginell, P. Afonine, O.N. Ventura, A. Cousido-Siah, M. Haertlein, A. Joachimiak, D. Myles, and A. Podjarny, (2008). Proc. Nat. Acad. Sci. USA 105 (6), 1844-1848
A preliminary neutron crystallographic study of thaumatin, S.C.M. Teixeira, M.P. Blakeley, R.M.F. Leal, E.P. Mitchell and V.T. Forsyth, (2008). Acta Cryst. F64, 378-381 [doi:10.1107/S1744309108008294].
Complementing structural information of modular proteins with small angle neutron scattering and contrast variation, J.G. Grossmann, A.J. Callaghan, M. J. Marcaida, B.F. Luisi, F.H. Alcock, K. Tokatlidis, M. Moulin, M. Haertlein, P. Timmins, (2008). Eur. Biophys. J. 37, 603-611.
Solvent isotope effect on macromolecular dynamics in E. coli, Jasnin M, Tehei M, Moulin M, Haertlein M, Zaccai G., (2008). Eur. Biophys. J. 37, 613-617.
X-ray and Neutron Small-Angle Scattering Analysis of the Complex Formed by the Met Receptor and the Listeria monocytogenes Invasion Protein InlB, Niemann HH, Petoukhov MV, Härtlein M, Moulin M, Gherardi E, Timmins P, Heinz DW, Svergun DI., (2008) J. Mol. Biol. 377, 489-500.
Coincidence of Dynamical Transitions in a Soluble Protein and Its Hydration Water: Direct Measurements by Neutron Scattering and MD Simulations, Wood K, Froelich A, Paciaroni A, Moulin M, Haertlein M, Zaccai G, Tobias GJ, Weik M, (2008). J. Am. Chem. Soc. 130, 4586-4587.
Down to atomic scale intracellular water dynamics, Jasnin M, Moulin M, Haertlein M, Zaccai G, Tehei M, (2008) EMBO Reports 9, 545-547.

2007

Coupling of protein and hydration water dynamics in biological membranes, Wood, K., P. lazanet, M., Kessler, B., Gabel, F., Oesterhelt, D., Tobias, D., Zaccai, G. & Weik, M., (2007) Proc. Natl. Acad. Sci. USA 104, 18049-18054 [DOI pnas.0706566104].
NMR Crystallography: The effect of deuteration on high resolution 13C solid state NMR spectra of a 7-TM protein, K. Varga, L. Aslimovska, I.M. Parrot, M.-T. Dauvergne, M. Haertlein, V.T. Forsyth, A. Watts, Biochim. Biophys. Acta. 1768, 3029-3035 (2007). Adaptation to high temperatures through macromolecular dynamics by neutron scattering, Tehei, M., and Zaccai, G., (2007) FEBS Journal 274, 4034–4043.
Shape and subunit organisation of the DNA methyltransferase M.Ahdl, Callow, P., Sukhodub, A., Taylor, J., Kneale, G., J. Mol. Biol. 69, 177-185 (2007). A methodology and an instrument for the temperature-controlled optimization of crystal growth, Budayova-Spano, M. , Dauvergne,F., Audiffren, M., Bactivelane, T., Cusack, S., (2007) Acta Cryst. D63, 339–347.
Neutron scattering reveals extremely slow cell water in a Dead Sea organism. M. Tehei, B. Franzetti, K. Wood, F. Gabel, E. Fabiani, M. Jasnin, M. Zamponi, D. Oesterhelt, G. Zaccai, M. Ginzburg and B.-Z. Ginzburg (2007). PNAS, 104(3), 687-1104.
A methodology and an instrument for the temperature-controlled optimization of crystal growth. M. Budayova-Spano, F. Dauvergne, M. Audiffren, T. Bactivelane and S. Cusack. (2007). Acta Cryst. D63, 3, 339-347.
The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase. X. Liu, B. L. Hanson, P. Langan and R.E.Viola (2007). Acta Cryst. D63, 1000-1008.
Expression, purification, assay, and crystal structure of perdeuterated human arginase I. Di Costanzo, L., Moulin, M., Haertlein, M., Meilleur, F., Christianson, D.W (2007). Arch. Biochem. Biophys. 465(1), 82-89.
Adaptation to high temperatures through macromolecular dynamics by neutron scattering, Tehei, M., and Zaccai, G. (2007). FEBS Journal 274, 4034–4043.
Shape and subunit organisation of the DNA methyltransferase M.Ahdl, Callow, P., Sukhodub, A., Taylor, J., Kneale, G., (2007). J.Mol. Biol. 69 (1), 177-185.
Neutron scattering reveals extremely slow cell water in Dead Sea organisms, Tehei, M., Franzetti, B., Wood, K., Gabel, F., Fabiani, E., Jasnin, M., Zamponi, M., Oesterhelt, D., Zaccai, G., Ginzburg, M., Ginzburg, B.-Z. (2007). Proc. Nat. Acad. Sci 104 (3), 766-771.

2006

Structural studies on acridine derivatives binding to telomeric DNA. Miles, S., Callow, P., Teixeira, S.C.T., Gan, Y., Denny, W., Cardin, C., Forsyth, V.T. (2006). Physica B 845, 385-386.
Efficient characterization of protein secondary structure in terms of screw motions, G.Kneller, P.Calligari (2006). Acta Cryst D62, 302-311.
A preliminary neutron diffraction study of Rasburicase, recombinant urate oxidase enzyme, complexed with 8-azaxanthin. Budayova-Spano M., Bonneté F., Ferté N., El Hajji M., Meilleur F., Blakeley M., Castro B. (2006). Acta Cryst. F62, 306-309.
High-Angle Neutron Fibre Diffraction in the Study of Biological systems.Forsyth, V.T., and Parrot, I.M. (2006). Neutron Scattering in Biology - Techniques and Applications, Springer Series on Biological and Medical Physics/Biomedical Engineering, Eds Fitter, J., Gutberlet, T., Katsaras, J.
Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II. Budayova-Spano, M., Zoe Fisher, S., Dauvergne, M.-T., Agbandje-McKenna, M., Silverman, D.N., Myles, D., McKenna, R. (2006). Acta Cryst. F62, 4-9.
Discovering New Classes of Brugia malayi Asparaginyl tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change. S. C. K. Sukuru, T. Crepin, Y. Milev, L. C. Marsh, J. B. Hill, R. J. Anderson, J. C. Morris, A. Rohatgi, G. O'Mahony, M. Grotli, F. Danel, Y. Milev, M. G. P. Page, M. Hartlein, S. Cusack, M. A. Kron, and L. A. Kuhn. (2006). J. Comp.-Aided Mol. Design 20(3): 159-178 (DOI 10.1007/s10822-006-9043-5).
Brugia malayi asparaginyl-Transfer RNA synthetase Induces Chemotaxis of human leucocytes and activates G-protein-coupled receptors CXCR1 and CXCR2. Ramirez, B.L., Howard, O.M., Dong, H.F., Edamatsu, T., Gao, P., Haertlein, M., Kron, M. (2006). J. Infec. Dis. 193 (8), 1164-71.
X-rays and neutrons for the study of DNA structure, transitions and hydration. Parrot, I.M., Laux, V., Urban, V., Haertlein, M., Forsyth, V.T. (2006). Physica B 848, 385-386.
Neutrons in biology: Institut Laue - Langevin, 4-7 September 2005, Deme B, Forsyth T, Fragneto G, Hartlein M, May R, Timmins P, Zaccai G., Eur Biophys J. (2006), 35(7):549-50.

2005

Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Meilleur F, Dauvergne MT, Schlichting I, Myles D.A. (2005). Acta Cryst. D61(5), 539-44.
Protonation states in human aldose reductase observed with high resolution X-ray crystallography and preliminary neutron diffraction results, Blakeley M., Hazemann, I. Mitschler, A., Meilleur, F., Dauvergne, Haertlein, M, El-Kabbani, O., Cousido, A., van Zandt, M., Oka, M., Joachimiak, A., Petrova, T., Myles, D.A.A.,Podjarni, A.D., Chapter 2, Neutron Crystallography, 87-102, In Hydrogen- and Hydration-Sensitive Structural Biology, Eds. Nimura, N. Mizuno, H., Helliwell, J.R.and Westhof, E.
High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase. Hazemann I, Dauvergne MT,Blakeley MP, Meilleur F, Haertlein M, Van Dorsselaer A, Mitschler A, Myles D.A., Podjarny A. (2005). Acta Cryst. D61, 10, 1413-7.
Real time characterization of intermediates in the pathway to open complex formation by RNA polymerase. Sclavi, B., Zaychikov, E., Rogozina, A., Walther, F., Buckle, M.,Heumann, H. (2005). PNAS 102, 4706-4711.
Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study. Gabel, F., Weik, M., Masson, P., Renault, F., Fournier, D., Brochier, L., Doctor, B., Saxena, A., Silman, I. & Zaccai, G. (2005). Biophys J. 89(5), 3303-11.
Liquid-like water confined in stacks of biological membranes at 200 k and its relation to protein dynamics. Weik, M., Lehnert, U. & Zaccai, G. (2005). Biophys J., Biophys J. 89(5), 3639-46.
Etudes par diffraction de fibres de l’ADN double brin. Forsyth, V.T. and Parrot, I.M. (2005). Journal de Physique IV, 130, 63-74.
Combined X-ray and Neutron Fibre Diffraction Studies of Biological and Synthetic Polymers. Parrot, I.M., Urban, V., Gardner, K.H., Forsyth, V.T.(2005). Nucl. Instr. Meth. in Phys. Res., B238, 7-15.
Neutron scattering reveals the dynamic basis of protein adaptation to extreme temperature. Tehei, M., Madern, D., Franzetti, B., Zaccai, G. (2005). J Biol Chem. 9, 280(49), 40974-9.
A comparison of refined X-ray structures of hydrogenated and perdeuterated ray gamma E crystallin in H2O and D2O. Artero, J.B., Hartlein, M., McSweeny, S., Timmins, P.A. (2005). Acta Cryst. D61, 1541-1549.
Do tissue levels of autoantigenic aminoacyl-tRNA synthetase predict clinical disease? Kron, M.A., Petridis, M., Haertlein, M., Libranda-Ramirez, B., Scaffidi, L.E. (2005). Med Hypotheses, 65(6), 1124-7.
Aminoacyl-tRNA Synthetases and Disease in the Aminoacyl-tRNA synthetases, Kron M, Härtlein M. Landes Biosciences Publishers. Eds: Michael Ibba, Christopher Franklyn and Stephen Cusack. (2005).

2004

Water-DNA interactions by x-ray and neutron fibre diffraction. Fuller, W., Forsyth, V.T., Mahendrasingam, A. (2004). Phil. Trans. Roy. Soc. 359, 1448, 1237-1248.
Structural stability and dynamics of hydrogenated and perdeuterated cytochrome P450cam (CYP101). Meilleur F, Contzen J, Myles DA, Jung C. (2004). Biochemistry 13, 8744-53.

2003

Expression, Localization and Alternative Function of asparaginyl-tRNA synthetase
in Brugia malayi. M. Kron, M. Petridis, Y. Milev, J Leykam, M Härtlein. (2003), Molecular and Biochemical Parasitology, 129 (1), 33-39
Strategies for antifilarial drug development, Kron M, Kuhn L, Sanschagrin , P.C., M Härtlein, Grotli M and Cusack S. (2003), J Parasitology 89(Suppl.) S226-S235