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small-angle neutron scattering (SANS), designed for the study of large scale structures in chemistry, biology and solid state physics. The animation shows how measurements are performed.

the instrument This video was recorded on Oct, 2006 during an experiment intitled "Light-induced biological-function related dynamics in bacteriorhodopsin (purple membrane)". The unusual environment setup

of phosphorus and oxygen to a specific location on a substrate protein to activate its specific biological function. Problems arise when gene mutations occur that cause kinases to work improperly, which ... energy.gov/ . LADI-III is a quasi-Laue neutron diffractometer used for single-crystal studies of biological macromolecules at high resolution ...

to probe materials.  The fields of investigation range from technology applications to biology and health. Neutrons hold the key to many important questions related to the fundamental laws

highlights how neutrons are an unrivaled probe for identifying the location of hydrogen atoms in biological systems, providing us with an unprecedented level of structural detail for this important enzyme ... the paper’s lead co-author and a doctoral student at the University of Toledo, works in ORNL’s Biology and Soft Matter Division as part of ...

For many biological fibres (eg DNA, polysaccharides, filamentous viruses), water is a key environmental parameter. The amount of H 2 O in the sample and the H 2 O/D 2 O substitution in biological samples ... addition to its mainstream single crystal applications, D19 is unique for high-resolution studies of biological and industrial fibres; here ...

stal neutron diffraction studies of biological macromolecules at high resolution (1.5 - 2.5Å). - Visualisation of key hydrogen or deuterium atoms within biological macromolecules, identifying the protonation ... Morphologies of superalloys; Microporosity in ceramics; Interfaces and surfaces of catalysts - Biological macromolecules - Size and shape ...

including polymers, ceramics, composites, glass, and biological samples. In addition to the wide range of applications, from materials science to biology, this technique can be operated in a number of en ... scientific processes, such as detergency, formulations in pharmacy or cosmetics, biomembranes, biological systems, etc. Therefore, it is very ...

Condensed Matter (PSCM) , procedures for the separation, purification and analysis of small, deuterated biological molecules derived from cell cultures, which will complement the macromolecular deuteration capabilities ... develop methods for the separation and purification of: • Main amphiphilic lipid components of biological membranes • Raft ...

for several years to provide our users with well-characterized membrane models for physical and biological studies. While phospholipid deuteration helps elucidate membrane structure, dynamics and function ... involving deuterated biomimetic membranes are currently limited by the low availability of several biologically relevant unsaturated ...