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water H-bonding that respect these essential biological properties. Neutrons are the ideal tool for investigating structure and dynamics in water and biological molecules– they have a number of unique advantages ... groups, scientists contribute to the newest findings in the areas of biochemistry, cell biology, structural biology, biophysics and ...

technologies, structural biology and bioenergy. At Oak Ridge, Paul’s first assignments were as Director of the Center for Structural Molecular Biology and Director of the Biology and Soft Matter Division ... fundamental particle physics, gamma irradiation and materials activation analysis. Other assignments in biology, chemistry and physics have ...

multiple tasks, including the remodelling of the cellular proteome, i.e. the ensemble of proteins in a biological cell. A subfamily, so-called unfoldases, recognize, unfold, and address misfolded or dysfunctional ... transient character of the interaction with their protein substrates, it is challenging in structural biology to follow the ...

studies of biological and industrial fibres. Applications Single crystal Organometallic complexes Hydrogen-bonded systems Mineral composition Changes of structure with temperature Biological molecules and

soft matter on D11 , biology on D22 and magnetism on D33 . Contrast variation based on isotopic substitution (normally hydrogen → deuterium) is widely used in soft matter and biology studies – support can ... molecules. SANS is a ver important technique applied to many different systems: polymers, colloids, biological macromolecules, emulsions, ...

scattering (SANS), designed for the study of large scale structures in soft matter systems, chemistry, biology, solid state physics and materials science. It has received a new 3 He multi-tube (Reuter-Stokes) ... coherent-to-incoherent signal, such as occurs in contrast-variation SANS (CV-SANS), especially for biological samples. The new ...

The BDCS group (Biology, Deuteration, Chemistry and Soft Matter) operates/develops user platforms that aim to enhance the quality, scope and throughput of neutron scattering studies of the structure and ... and dynamics of biological systems. One key issues of importance is deuterium labelling, which is of primary importance to small-angle neutron ...

with studies addressing a variety of important biological processes from protein-folding to antibiotic resistance and proton transport across biological membranes. Instrument: Quasi-Laue diffractometer ... of deuterated HIV-1 protease was provided by the Center for Structural Molecular Biology ( CSMB ), DOE Office of Biological and Environmental ...

to biological samples. We study molecular dynamics and structure at the atomic level and try to relate them to the functionality of biological systems. In particular, I am interested in biological systems

experiments at the cutting edge of research for more than 40 years now, in fields as varied as molecular biology, chemistry, fundamental physics, materials science and the environment. The examples of science in ... brochure . These examples illustrate the power of neutrons in many areas of science. Advanced materials Biology Chemistry Magnetism ...