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water H-bonding that respect these essential biological properties. Neutrons are the ideal tool for investigating structure and dynamics in water and biological molecules– they have a number of unique advantages ... groups, scientists contribute to the newest findings in the areas of biochemistry, cell biology, structural biology, biophysics and ...

multiple tasks, including the remodelling of the cellular proteome, i.e. the ensemble of proteins in a biological cell. A subfamily, so-called unfoldases, recognize, unfold, and address misfolded or dysfunctional ... transient character of the interaction with their protein substrates, it is challenging in structural biology to follow the ...

technologies, structural biology and bioenergy. At Oak Ridge, Paul’s first assignments were as Director of the Center for Structural Molecular Biology and Director of the Biology and Soft Matter Division ... fundamental particle physics, gamma irradiation and materials activation analysis. Other assignments in biology, chemistry and physics have ...

scattering (SANS), designed for the study of large scale structures in soft matter systems, chemistry, biology, solid state physics and materials science. The instrument received a new 3 He multi-tube (Reuter-Stokes) ... coherent-to-incoherent signal, such as occurs in contrast-variation SANS (CV-SANS), especially for biological samples. The new ...

The BDCS group (Biology, Deuteration, Chemistry and Soft Matter) operates/develops user platforms that aim to enhance the quality, scope and throughput of neutron scattering studies of the structure and ... and dynamics of biological systems. One key issues of importance is deuterium labelling, which is of primary importance to small-angle neutron ...

with studies addressing a variety of important biological processes from protein-folding to antibiotic resistance and proton transport across biological membranes. Instrument: Quasi-Laue diffractometer ... of deuterated HIV-1 protease was provided by the Center for Structural Molecular Biology ( CSMB ), DOE Office of Biological and Environmental ...

experiments at the cutting edge of research for more than 40 years now, in fields as varied as molecular biology, chemistry, fundamental physics, materials science and the environment. The examples of science in ... the power of neutrons in many areas of science. Magnetism and quantum materials Soft matter and Biology Chemistry and Materials ...

to biological samples. We study molecular dynamics and structure at the atomic level and try to relate them to the functionality of biological systems. In particular, I am interested in biological systems

means dimensions of a few tenths to about 100 nanometres, such as clusters in alloys, polymers, or biological macromolecules. In general, these structures are disordered. The high neutron flux and the flexibility ... morphologies of superalloys, microporosity in ceramics, interfaces and surfaces of catalysts) Biological macromolecules (size and ...

of model and biological membranes and the capacity to host in parallel a very diverse community in other scientific fields. D16 applications range over a very large number of fields: biology (model and ... biological membrane multilayers), soft condensed matter (colloids, liquid crystals, polymers and surfactants), chemistry and material science ...