membrane-active structured-oligomer state, and 2) when early, unstructured Aβ peptide forms are administered and peptide oligomerisation possibly takes place at the membrane. Both showed membrane-active species
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could account for the hourglass spectrum. This is particularly interesting as it links two highly active research fields that of superconductivity and that of frustrated magnetism. Instrument: IN8 - Three-axis
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that changes in amino-acid protonation-states distant from the active-site can trigger a change in hydrogen configuration in the active-site may apply to other aspartic proteases, and perhaps enzymes ... of HIV-1 protease/drug complexes, providing key details of hydrogen-bonding interactions in the active-site and revealing a pH-induced proton ...
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enzyme, a vitamin B6-dependent protein, and found that the chemical reaction occurred only in one active site. Nuclear scattering length density maps (colored mesh) highlight the positions of critical hydrogen ... design.” The team’s previous research predicted that hydrogen atoms move in and around the enzyme’s active site, where the chemical ...
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together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. (Image: ... structure as well as the protonation states of all amino acids in PKA and the ligands bound to its active site, many of which were previously ...
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solid samples which can be tilted using one of the sample goniometers. The sample area includes an active anti-vibration table and free liquid surfaces are aligned automatically using an optical device.
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diffractometer for biology Reference: Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase, https://doi.org/10.1016/j.xcrp
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the sublattices cancel.” The spin dynamics at and around the compensation temperatures is thus an active area of research. It is expected that future polarised neutron inelastic scattering experiments on
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transmission performance has also improved, and the device will be free from radiation damage and activation issues in the future. “This is the last stage of the development – the polarisation efficiency
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tube IH3), then on PF2 Level D). Today, the areas of research and techniques he pioneered are still active and new instruments are trying to go even further. Ramsey's PhD students and collaborators at the
Pertinence: 27%