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Study of macromolecular systems using the wide range of technology platforms available in the Partner for Structural Biology, including neutron and X-ray diffraction.

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The Life Sciences Group

The Life Sciences Group is located in the Carl-Ivar Brändén Building (CIBB) and focuses on the study of macromolecular systems using the wide range of technology platforms available in the Partnership for Structural Biology, including neutron and X-ray diffraction. The group has advanced capabilities in molecular biology, biochemistry, isotope labelling, and contains a dedicated Deuteration Laboratory (D-Lab) for which user access can be sought through a rapid access peer-review proposal system. The group is also developing a crystallogenesis platform, with a specific focus on the large crystal growth needs of neutron protein crystallography for instruements such as LADI-III and D19.


The group has a number of  in-house research activities, many  of which are collaborative with member of the international user community; essentially all these involve close cooperation with the ESRF Structural  Biology Group and the Business Development Unit. The collaborations include host-pathogen interactions (eg malaria, HIV), amyloid structure and assembly, membrane-protein interactions, as well as technical developments for selective and non-selective isotope labelling of proteins, peptides, nucleic acids etc. Collaborations relating to these projects exits with Bristol University, Keele University, Unversite Joseph Fourier (UJF), Wits University Medical School (South Africa), University College London (UCL).