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While the ILL's neutron source has remained essentially unchanged during the lifetime of the Institute, the ILL's instruments and their components have been continually developed and improved to increase their effectiveness.

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The Soft Matter Science and Support (SMSS) group is located in the Science Building and has the responsibility for running the Chemistry Laboratories, on the first floor, and the Partnership for Soft Condensed Matter (PSCM) initiative on the second floor. It operates in close collaboration with the LSS group. Besides the laboratory responsibles it hosts a large number of PhD students and post-docs either with ILL or external grant fundings working on soft matter science using neutron scattering. It has also the responsibility for setting up a deuterated lipid extraction facility currently funded by the SINE2020 grant and in collaboration with the D-Lab.