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Investigating cyan fluorescent proteins for bioimaging with neutron experiments

For the past 25 years, scientists have been developing fluorescent proteins for bioimaging. Today their diversity covers nearly the whole visible spectrum, including blue, cyan, green, yellow, orange, red, far-red and near infrared, allowing scientists to produce detailed images of various proteins’ localization within live cells using multicolour labelling.

(Left) Structure of a Cyan Fluorescent Protein represented with the fluorescent chromophore (cyan) and the beta-strand shown to be variably flexible (yellow). (Right) Mean square position fluctuations of four Cyan Fluorescent Proteins.