30 mars 2021
Un sucre au deutérium pour étudier l’amarrage des bactéries sur nos cellules
Infos
12 août 2020
Following protein aggregation in real time by neutron spectroscopy
August 2020Protein aggregation into amyloid superstructures is the molecular manifestation of a large variety of neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Evidence is increasing that transient on-pathway oligomers are actually the toxic species, such that time-resolved monito…
27 juillet 2020
Magnetic nanoparticles change their magnetic structure in a magnetic field
Schematic representation of the homogeneously magnetized core of ferrite nanoparticles. As the external magnetic field is increased, the magnetic volume grows, eventually becoming 20% larger by volume than the coherent core.
July 2020When ultrafine magnetic partic…
19 novembre 2019
Scientists reveal key protein molecules associated with the unique water purification properties of Moringa seeds
Moringa seeds
November 2019One in three people cannot access clean drinking water [1]. Moringa seed extracts have been used of centuries to help purify water in regions where clean water is not available.Researchers have used neutrons and X-rays to identify …
30 septembre 2019
Record-Fast Neutron Tomography on D50 Tracks Water Pathways into Plants
5 juin 2019
Neutrons shining light on the structure of silk-derived biomaterials
Silk may well be the oldest biomaterial humans have exploited. The primary protein comprising silk is fibroin, and in the last century, it has been intensely studied for a variety of advanced applications beyond luxurious fabrics. Some of the most exciting current research is exploring the potential of this protein in a range of applications using neutrons.
15 avril 2019
Investigating cyan fluorescent proteins for bioimaging with neutron experiments
For the past 25 years, scientists have been developing fluorescent proteins for bioimaging. Today their diversity covers nearly the whole visible spectrum, including blue, cyan, green, yellow, orange, red, far-red and near infrared, allowing scientists to produce detailed images of various proteins’ localization within live cells using multicolour labelling.
26 mars 2019
Neutron experiments reveal proteins which can inhibit amyloid plaque formation
New clues about the molecular nature of Alzheimer’s disease
21 mars 2019
Neutrons paint atomic portrait of prototypical cell signaling enzyme—protein kinase A
Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders
26 février 2019
Researchers unravel information about a protein causing progressive diseases
The C-D loop in transthyretin is tight in the stable T119M mutant (protective against amyloidosis). However, the same loop at the mutation site of the S52P mutant (associated with the most aggressive form of transthyretin amyloidosis) is loosened, causing degradation of the protein and misfolding…
27 novembre 2018
Insights into magnetic bacteria may guide research into medical nanorobots
• Magnetotactic bacteria are a unique aquatic species which use magnetic nanoparticles as an internal compass to navigate • The configuration of the magnetic chain in these bacteria has been analysed using neutrons, explaining how the magnetic field affects its behaviour • Understanding t…
23 octobre 2018
Des interactions à la surface externe d’E.coli analysées grâce aux neutrons
Image de micrographie électronique à balayage d'Escherichia coli
• Les infections bactériennes sont potentiellement mortelles (6 millions de décès par an sont causés par un sepsis, ou infection du sang) et deviennent de plus en plus résistantes aux antibiot…