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News

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Feb. 29, 2024 Neutrons, space-grown crystals, and enzymes
An article recently published in Cell Reports reveals how researchers have for the first time directly visualized the position of protons within key functional elements of an enzyme that plays an important role in the metabolism of many microorganisms. Neutron diffraction measurements at ILL of protein crystals grown under microgravity conditions at the International Space Station (ISS) were key ingredients in this work.
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May 12, 2023 Neutron scattering and selective deuteration reveal the structure and composition of mRNA-containing LNPs and the effects induced by the serum protein ApoE
The serum protein ApoE is known to bind to LNPs after administration and to be critical for cellular uptake and protein production in the liver. The acquisition of complementary SANS and SAXS data revealed the structural and compositional effects induced by this binding: a rearrangement of both t…
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Sept. 23, 2021 PRISMAP – The European medical radionuclides programme sets out to transform the European landscape for novel and emerging medical radionuclides
Medical isotope collection at CERN MEDICIS; ©CERN 2018-2021 Nuclear therapy and molecular imaging, which are widely used in hospitals for promising new medical procedures, can drastically improve outcomes for many medical conditions, making it possible to treat dis…
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July 24, 2018 Key binding characteristics of a sugar-binding protein associated with heart disease and breast cancer defined for the first time, guiding future drug development
Key binding characteristics of a sugar-binding protein associated with heart disease and breast cancer defined for the first time, guiding future drug developmentResearchers pinpoint hydrogen-bonding interactions in the C-terminal carbohydrate recognition domain of galectin-3 (galectin-3C) for the first time using neutron crystallographyThese detailed observations will inform future drug design f…